20 dimensions of 'nuisance parameters' over several different channels of data.
RooFit, RooStats - toolkit for determining expected values of some physical process.
Primarily frequentist, some Bayesian but there is a general dislike for assigning prior probabilities to theoretical particles not yet observed.
"Bayesian probability allows prior knowledge and logic to be applied to uncertain statements. Theres another interpretation called frequency probability, which only draws conclusions from data and doesnt allow for logic and prior knowledge." (ML in Action)
Inverse problems in X-ray scattering (Stefano Marchesini, Lawrence Berkeley National Laboratory, Photon Science)